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Cayo District, Belize
Macal River begins in the Cayo District, an inland jungle region in Belize, and flows into the Belize River. Guests at resorts along the river can canoe to the town of San Ignacio. Parts of the river flow into the region's limestone caves, where ancient Mayan rituals took place, and cave tubing is a popular tourist activity. Wildlife spotting along the river is excellent: There are howler monkeys, jaguars, toucans, and more. Oyster's Pick for Where to Stay: Chaa Creek, Belize

Think Beyond the Beach: 9 Lake and River Getaways(7 of 9)